Bottles of frozen blood plasma are brought to the machine in bins from a freezer where they are stored at -30C. The bins are loaded into a bin lifter and dumped into a feed system that discharges a single file line of bottles to an orientation station. The bottles are oriented and fed into a pre-wash conveyor which rinses the outside of the bottles for 30 seconds and presents them to the entrance of 16 rotating thawing tubes. The 16 bottles are then pushed into the thawing tubes. The thawing tubes are rotated at 200 rpm and warm water is injected to thaw the plasma. This agitates the bottle to slowly and uniformly thaw the plasma without any of the plasma exceeding a temperature or 6C during the process. From the thawing tubes the bottles are loaded into nests on an indexed carousel where the exterior of the bottles is washed again, dried, and sterilized with UV light.